Hubungan ekspresi Tumor Necrosis Factor Alpha (TNF-α) dengan destruksi tulang akibat kolesteatoma
نویسندگان
چکیده
منابع مشابه
TUMOR NECROSIS FACTOR ALPHA (TNF-a)
Tumor necrosis factor alpha (TNF, TNFSF2) is an important multifunctional cytokine that regulates inflammation, host defense, immune responses, and apoptosis. TNF exists as a membrane-bound 26kDa, type II integral membrane protein, and a 17kDa soluble homotrimeric TNF that is generated via proteolytic cleavage by TNF-a converting enzyme (TACE, ADAM17). Both the membrane-bound and soluble forms ...
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Background The pro-inflammatory cytokine, tumor necrosis factor-alpha (TNF-α), is a pathogenic element for a number of disorders. Previous studies have reported that the -1031 T/C and -238 G/A polymorphisms in the promoter region of the TNF-α gene are important factors in reproductive-related disorders. One of the most common gynecological diseases of women during the reproductive years is endo...
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The monocyte/macrophage-derived cytokine, Tumor Necrosis Factor Alpha (TNF-α) plays a central role in effective granulomatous immunity to Mycobacterium tuberculosis infections in humans. The present study was conducted to document changes in the serum TNF-α level of patients after varying durations of anti-tuberculous therapy as compared to normal healthy controls. A comparative study was condu...
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PURPOSE Tumor necrosis factor alpha (TNF-α), a macrophage/monocyte derived pluripotent cytokine is associated with tissue ischemia, neuronal damage and remodeling. The physiological level of TNF-α in aqueous humor of normal and glaucomatous eyes is unknown. In this study, we evaluated the TNF-α levels in aqueous in patients with primary open angle glaucoma (POAG) and compared them to controls. ...
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The aim of this study was to develop a human tumor necrosis factor alpha (hTNF-α) ELISA system because specific and sensitive measurement of low levels of circulating TNF-α is very important for enlightening the immunopathologial mechanisms associated with TNF-α. Monoclonal antibodies 6A4c and 8A6 were produced against hTNF-α and were used as the capture antibody and the tracer antibody respect...
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ژورنال
عنوان ژورنال: Oto Rhino Laryngologica Indonesiana
سال: 2015
ISSN: 2598-3970
DOI: 10.32637/orli.v45i1.104